Structural Insights into Drug Processing by Human Carboxylesterase 1: Tamoxifen, Mevastatin, and Inhibition by Benzil

Author:

Fleming Christopher D.,Bencharit Sompop,Edwards Carol C.,Hyatt Janice L.,Tsurkan Lyudmila,Bai Feng,Fraga Charles,Morton Christopher L.,Howard-Williams Escher L.,Potter Philip M.,Redinbo Matthew R.

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference55 articles.

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2. The mammalian carboxylesterases: from molecules to functions;Satoh;Annu. Rev. Pharmacol. Toxicol.,1998

3. Human carboxylesterase 1: from drug metabolism to drug discovery;Redinbo;Biochem. Soc. Trans.,2003

4. Binding and hydrolysis of meperidine by human liver carboxylesterase hCE-1;Zhang;J. Pharmacol. Expt. Ther.,1999

5. Variable activation of lovastatin by hydrolytic enzymes in human plasma and liver. 4;Tang;Eur. J. Clin. Pharmacol.,1995

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