Structural Snapshots of MTA/AdoHcy Nucleosidase Along the Reaction Coordinate Provide Insights into Enzyme and Nucleoside Flexibility During Catalysis

Author:

Lee Jeffrey E.,Smith G.David,Horvatin Cathy,Huang David J.T.,Cornell Kenneth A.,Riscoe Michael K.,Howell P.Lynne

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference46 articles.

1. A hydrolytic nucleosidase acting on S-adenosylhomocysteine and on 5′-methylthioadenosine;Duerre;J. Biol. Chem.,1962

2. Methionine recycling pathways and antimalarial drug design;Sufrin;Antimicrob. Agents Chemother.,1995

3. Methionine recycling as a target for antiprotozoal drug development;Riscoe;Parasitol. Today,1989

4. Biological Methylation and Drug Design-Experimental and Clinical Roles of S-adenosylmethionine;Borchardt,1986

5. Methylthioadenosine, a potent inhibitor of spermine synthase from bovine brain;Pajula;FEBS Letters,1979

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