A Structural Comparison of Inhibitor Binding to PKB, PKA and PKA-PKB Chimera-Reference-Cited by-同舟云学术

A Structural Comparison of Inhibitor Binding to PKB, PKA and PKA-PKB Chimera

Published:2007-03 Issue:3 Volume:367 Page:882-894
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Davies Thomas G.,Verdonk Marcel L.,Graham Brent,Saalau-Bethell Susanne,Hamlett Christopher C.F.,McHardy Tatiana,Collins Ian,Garrett Michelle D.,Workman Paul,Woodhead Steven J.,Jhoti Harren,Barford David

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference53 articles.

1. Inhibition of protein kinase B/Akt. implications for cancer therapy;Hill;Pharmacol. Ther.,2002

2. Ten years of protein kinase B signalling: a hard Akt to follow;Brazil;Trends Biochem. Sci.,2001

3. Advances in protein kinase B signalling: AKTion on multiple fronts;Brazil;Trends Biochem. Sci.,2004

4. PI3K/Akt signalling pathway and cancer;Vara;Cancer Treatment Rev.,2004

5. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα;Alessi;Curr. Biol,1997

Cited by 80 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Development of Novel Pyridine and Pyrimidine Clubbed Bisindoles as Inhibitors of AKT Pathway;ChemistrySelect;2024-07-17

2. Computer-Aided Identification of Kinase-Targeted Small Molecules for Cancer: A Review on AKT Protein;Pharmaceuticals;2023-07-11

3. Molecular docking appraisal of Dysphania ambrosioides phytochemicals as potential inhibitor of a key triple-negative breast cancer driver gene;In Silico Pharmacology;2023-06-14

4. Identification of novel inhibitors of P13K/AKT pathways: an integrated in-silico study towards the development of a new therapeutic agent against ovarian cancer;Physical Sciences Reviews;2023-05-25

5. Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy;ACS Omega;2023-05-24