Faster in vivo clearance of human embryonic kidney than Chinese hamster ovary cell derived protein: Role of glycan mediated clearance

Author:

Wang Mengmeng,Ishino Tetsuya,Joyce Alison,Tam Amy,Duan Weili,Lin Laura,Somers William S.,Kriz Ronald,O'Hara Denise M.

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference20 articles.

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2. Analysis of the pH dependence of the neonatal Fc receptor/immunoglobulin G interaction using antibody and receptor variants;Raghavan;Biochemistry,1995

3. Physiochemical and biochemical factors influencing the pharmacokinetics of antibody therapeutics;Bumbaca;AAPS J.,2012

4. High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans;Goetze;Glycobiology,2011

5. Studies of aglycosylated chimeric mouse-human IgG. Role of carbohydrate in the structure and effector functions mediated by the human IgG constant region;Tao;J. Immunol.,1989

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