Defining the Therapeutic Range for Adalimumab and Predicting Response in Psoriasis: A Multicenter Prospective Observational Cohort Study

Author:

Wilkinson Nina,Tsakok TeresaORCID,Dand Nick,Bloem Karien,Duckworth Michael,Baudry David,Pushpa-Rajah Angela,Griffiths Christopher E.M.,Reynolds Nick J.,Barker Jonathan,Warren Richard B.,Burden A. David,Rispens Theo,Stocken Deborah,Smith Catherine

Funder

PSORT

Medical Research Council

MRC Clinical Research Training Fellowship

Publisher

Elsevier BV

Subject

Cell Biology,Dermatology,Molecular Biology,Biochemistry

Reference22 articles.

1. Steady-state pharmacokinetics (PK) of adalimumab (HUMIRA (TM), Abbott) following 40 mg subcutaneous (sc) injection every other week (eow) in rheumatoid arthritis (RA) patients with and without methotrexate (MTX) background therapy;Awni;Arthritis Rheum,2003

2. Influence of immunogenicity on the long-term efficacy of infliximab in Crohn’s disease;Baert;N Engl J Med,2003

3. Prior response to infliximab and early serum drug concentrations predict effects of adalimumab in ulcerative colitis;Baert;Aliment Pharmacol Ther,2014

4. Significant associations of antidrug antibody levels with serum drug trough levels and therapeutic response of adalimumab and etanercept treatment in rheumatoid arthritis;Chen;Ann Rheum Dis,2015

5. The immunogenicity of anti-TNF therapy in immune-mediated inflammatory diseases: a systematic review of the literature with a meta-analysis;Garces;Ann Rheum Dis,2013

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