Coenzyme Q10 attenuates lung and liver fibrosis via modulation of autophagy in methotrexate treated rat

Author:

Mohamed Doaa I.,Khairy Eman,Tawfek Sherin Shafik,Habib Eman K.,Fetouh Marwa A.

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference50 articles.

1. Involvement of epithelial-mesenchymal transition in methotrexate-induced pulmonary fibrosis;Ohbayashi;J. Toxicol. Sci.,2014

2. Autophagy induction contributes to the resistance to methotrexate treatment in rheumatoid arthritis fibroblast-like synovial cells through high mobility group box chromosomal protein 1;Xu;Arthritis Res. Ther.,2015

3. Methotrexate hepatotoxicity is associated with oxidative stress, and down-regulation of PPARγ and Nrf2: Protective effect of 18γ -Glycyrrhetinic acid;Mahmoud;Chem. Biol. Interact.,2017

4. Gulcin I. Antioxidant activity of food constituents-An overview Archives of Toxicology, 86(3) 345-391.

5. In vivo antioxidant treatment protects against bleomycin induced lung damage in rats;Serrano-Mollar;Br. J. Pharmacol.,2003

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