Targeting NLRP3 inflammasome via acetylsalicylic acid: Role in suppressing hepatic dysfunction and insulin resistance induced by atorvastatin in naïve versus alcoholic liver in rats

Author:

El-Kharashi Omnyah A.,El-Din Aly El-Waseef Dalia Alaa,Nabih Enas S.,Mohamed Doaa I.

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference52 articles.

1. NLRP3 inflammasomes link inflammation and metabolic disease;De Nardo;Trends Immunol.,2011

2. The inflammasome NLRs in immunity, inflammation, and associated diseases;Davis;Annu. Rev. Immunol.,2010

3. Caspase-8 as an effector and regulator of NLRP3 inflammasome signaling;Antonopoulos;J. Biol. Chem.,2015

4. Kahn metabolic syndrome: Is Nlrp3 inflammasome a trigger or a target of insulin resistance?;Mori;Nat. Med.,2011

5. The protective effect of pentoxifylline versus silymarin on the pancreas through increasing adenosine by CD39 in a rat model of liver cirrhosis: pharmacological, biochemical and histological study;Mohamed;Gene,2017

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