The C7-aminomethylpyrrolidine group rescues the activity of a thio-fluoroquinolone-Reference-Cited by-同舟云学术

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The C7-aminomethylpyrrolidine group rescues the activity of a thio-fluoroquinolone

Published:2019-05 Issue: Volume:160 Page:24-27
ISSN:0300-9084
Container-title:Biochimie
language:en
Short-container-title:Biochimie

Author:

Lentz Sarah R.C.,Chheda Pratik R.,Oppegard Lisa M.,Towle Tyrell R.,Kerns Robert J.,Hiasa Hiroshi^ORCID

Funder

National Institutes of Health (NIH)

NIH Predoctoral Training Program in Biotechnology

University of Iowa Center for Biocatalysis and Bioprocessing

NIH Predoctoral Training Program in Pharmacological Sciences

American Foundation for Pharmaceutical Education

Publisher

Elsevier BV

Subject

General Medicine,Biochemistry

Reference19 articles.

1. DNA topoisomerase II and its growing repertoire of biological functions;Nitiss;Nat. Rev. Canc.,2009

2. All tangled up: how cells direct, manage and exploit topoisomerase function;Vos;Nat. Rev. Mol. Cell Biol.,2011

3. New mechanistic and functional insights into DNA topoisomerases;Chen;Annu. Rev. Biochem.,2013

4. DNA topoisomerases as targets for antibacterial agents;Hiasa;Methods Mol. Biol.,2018

5. Exploiting bacterial DNA gyrase as a drug target: current state and perspectives;Collin;Appl. Microbiol. Biotechnol.,2011

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1. Introducing of novel class of pyrano[2,3-c]pyrazole-5-carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and prominent pharmacokinetic and CNS toxicity profiles supported by molecular dynamic simulation;Journal of Biomolecular Structure and Dynamics;2023-09-03

2. Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects;European Journal of Medicinal Chemistry;2022-01

3. 15.4.5 Quinolinones and Related Systems (Update 2022);Knowledge Updates 2022/3;2022

4. Identification of two novel type II topoisomerase mutations in Enterococcus spp. isolated from a hospital in China;Archives of Biological Sciences;2021

5. Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase;Bioorganic & Medicinal Chemistry;2020-05

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