Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species
Author:
Publisher
Elsevier BV
Subject
General Medicine,Biochemistry
Reference24 articles.
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2. Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells;Kim;Mol. Cell. Biol.,2002
3. Autocrine expression of activated transforming growth factor-beta(1) induces apoptosis in normal rat liver, Am;Schrum;J. Physiol Gastrointest. Liver Physiol,2001
4. Activation of caspase-8 in transforming growth factor-beta-induced apoptosis of human hepatoma cells;Shima;Hepatology,1999
5. Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism;Black;J. Hepatol,2004
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