The intracellular content of dihydrofolate reductase: possibilities for control and implications for chemotherapy

Author:

Bastow K.F.,Prabhu R.,Cheng Y-C.

Publisher

Elsevier BV

Subject

Cancer Research,Genetics,Molecular Biology,Molecular Medicine

Reference26 articles.

1. Relation of folic acid reductase to aminopterin ‘resistance’ in cultured mammalian cells;Hakala;J. Biol. Chem.,1961

2. Isolation and partial characterization of three methotrexate-resistant phenotypes from Chinese hamster ovary cells;Flintoff;Somat. Cell. Genet.,1976

3. An immunostaining technique to demonstrate the heterogeneity in dihydrofolate reductase in leukemic cells;Grill;ASCO Abstracts,1983

4. Gene amplification and drug resistance in cultured murine cells;Schimke;Science,1978

5. Rapid spontaneous dihydrofolate reductase gene amplification shown by fluorescence-activated cell sorting;Johnston,1983

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