Stereoselective determination of the CYP2C19 probe drug mephenytoin in human urine by gas chromatography–mass spectrometry
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry
Reference14 articles.
1. Genetic polymorphism of S-mephenytoin hydroxylation
2. Evidence That CYP2C19 is the Major (S)-Mephenytoin 4'-Hydroxylase in Humans
3. Human cytochrome P450s: selectivity and measurement in vivo
4. A methodological investigation on the estimation of the S-mephenytoin hydroxylation phenotype using the urinary S/R ratio
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4. Chiral separation strategy in polar organic solvent chromatography and performance comparison with normal-phase liquid and supercritical-fluid chromatography;Journal of Separation Science;2006-07
5. Enantiospecific separation and quantitation of mephenytoin and its metabolites nirvanol and 4′-hydroxymephenytoin in human plasma and urine by liquid chromatography/tandem mass spectrometry;Rapid Communications in Mass Spectrometry;2006
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