Enantiospecific separation and quantitation of mephenytoin and its metabolites nirvanol and 4′-hydroxymephenytoin in human plasma and urine by liquid chromatography/tandem mass spectrometry-Reference-Cited by-同舟云学术

Enantiospecific separation and quantitation of mephenytoin and its metabolites nirvanol and 4′-hydroxymephenytoin in human plasma and urine by liquid chromatography/tandem mass spectrometry

Published:2006 Issue:3 Volume:20 Page:463-472
ISSN:0951-4198
Container-title:Rapid Communications in Mass Spectrometry
language:en
Short-container-title:Rapid Commun. Mass Spectrom.

Author:

Jansson Britt,Elsherbiny Doaa,Simonsson Ulrika S. H.

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference24 articles.

1. Evaluation of Cytochrome P450 Probe Substrates Commonly Used by the Pharmaceutical Industry to Study in Vitro Drug Interactions

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1. Breaking the sensitivity limitations of cytochrome P450 oxidation product: Dansyl chloride derivatisation of 4-OH mephenytoin, a CYP2C19 metabolite and its application to in vitro CYP inhibition assay;Journal of Chromatography B;2015-05

2. Prediction of In Vivo Clearance and Associated Variability of CYP2C19 Substrates by Genotypes in Populations Utilizing a Pharmacogenetics-Based Mechanistic Model;Drug Metabolism and Disposition;2015-04-06

3. Chiral chromatographic resolution of antiepileptic drugs and their metabolites: a challenge from the optimization to the application;Biomedical Chromatography;2013-08-15

4. Chiral drug analysis using mass spectrometric detection relevant to research and practice in clinical and forensic toxicology;Journal of Chromatography A;2012-12

5. High-performance liquid chromatography–tandem mass spectrometry in the identification and determination of phase I and phase II drug metabolites;Analytical and Bioanalytical Chemistry;2008-03-15