The transcriptional profile of the kidney in Tsc2 heterozygous mutant Long Evans (Eker) rats compared to wild-type
Author:
Publisher
Elsevier BV
Subject
Health, Toxicology and Mutagenesis,Genetics,Molecular Biology
Reference42 articles.
1. Use of the spontaneous Tsc2 knockout (Eker) rat model of hereditary renal cell carcinoma for the study of renal carcinogens;McDorman;Toxicol. Pathol.,2002
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3. Promotion by sodium barbital induces early development but does not increase the multiplicity of hereditary renal tumors in Eker rats;Wolf;Carcinogenesis,2000
4. Predisposition to renal carcinoma in the Eker rat is determined bu {by}germ-line mutation of the tuberous sclerosis 2 (TSC2) gene;Yeung;Proc. Natl. Acad. Sci.,1994
5. A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer;Kobayashi;Nat. Genet.,1995
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2. Evidence that TSC2 acts as a transcription factor and binds to and represses the promoter of Epiregulin;Nucleic Acids Research;2014-04-19
3. Tandem affinity purification and identification of the human TSC1 protein complex;Acta Biochimica et Biophysica Sinica;2010-03-01
4. Tuberous sclerosis complex: disease modifiers and treatments;Current Opinion in Pediatrics;2008-12
5. Carcinogen-Specific Gene Expression Profiles in Short-term Treated Eker and Wild-type Rats Indicative of Pathways Involved in Renal Tumorigenesis;Cancer Research;2007-05-01
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