PCSK9 ablation attenuates Aβ pathology, neuroinflammation and cognitive dysfunctions in 5XFAD mice-Reference-Cited by-同舟云学术

PCSK9 ablation attenuates Aβ pathology, neuroinflammation and cognitive dysfunctions in 5XFAD mice

Published:2024-01 Issue: Volume:115 Page:517-534
ISSN:0889-1591
Container-title:Brain, Behavior, and Immunity
language:en
Short-container-title:Brain, Behavior, and Immunity

Author:

Vilella Antonietta^ORCID,Bodria Martina,Papotti Bianca,Zanotti Ilaria,Zimetti Francesca,Remaggi Giulia,Elviri Lisa,Potì Francesco,Ferri Nicola,Lupo Maria Giovanna,Panighel Giovanni,Daini Eleonora,Vandini Eleonora,Zoli Michele,Giuliani Daniela,Bernini Franco

Publisher

Elsevier BV

Subject

Behavioral Neuroscience,Endocrine and Autonomic Systems,Immunology

Reference63 articles.

1. HMGB1/RAGE/TLR4 axis and glutamate as novel targets for PCSK9 inhibitor in high fat cholesterol diet induced cognitive impairment and amyloidosis;Abuelezz;Life Sci.,2021

2. Proprotein Convertase Subtilisin/Kexin Type 9, Brain Cholesterol Homeostasis and Potential Implication for Alzheimer's Disease;Adorni;Front. Aging Neurosci.,2019

3. Alterations in microglial phenotype and hippocampal neuronal function in transgenic mice with astrocyte-targeted production of interleukin-10;Almolda;Brain Behav. Immun.,2015

4. Pretreatment With PCSK9 Inhibitor Protects the Brain Against Cardiac Ischemia/Reperfusion Injury Through a Reduction of Neuronal Inflammation and Amyloid Beta Aggregation;Apaijai;J. Am. Heart Assoc.,2019

5. Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor exerts greater efficacy than atorvastatin on improvement of brain function and cognition in obese rats;Arunsak;Arch. Biochem. Biophys.,2020

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1. Central innate immunization induces tolerance against post-traumatic stress disorder-like behavior and neuroinflammatory responses in male mice;Brain, Behavior, and Immunity;2024-11

2. E3 ubiquitin ligase MARCH1 reduces inflammation and pyroptosis in cerebral ischemia-reperfusion injury via PCSK9 downregulation;Mammalian Genome;2024-08-08

3. Targeting Oxidative Stress in Neurodegenerative Disorders: A Novel Role for PCSK9 Inhibition?;ACS Chemical Neuroscience;2024-07-18

4. Specific Mode Electroacupuncture Stimulation Mediates the Delivery of NGF Across the Hippocampus Blood–Brain Barrier Through p65-VEGFA-TJs to Improve the Cognitive Function of MCAO/R Convalescent Rats;Molecular Neurobiology;2024-07-12

5. PCSK9 inhibition attenuates alcohol-associated neuronal oxidative stress and cellular injury;Brain, Behavior, and Immunity;2024-07