Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP)

Author:

Bauer Lisa,Ferla SalvatoreORCID,Head Sarah A.,Bhat Shridhar,Pasunooti Kalyan K.,Shi Wei Q.ORCID,Albulescu Lucian,Liu Jun O.,Brancale AndreaORCID,van Kuppeveld Frank J.M.,Strating Jeroen R.P.M.ORCID

Funder

Netherlands Organisation for Scientific Research

European Union

PhRMA Foundation

US National Cancer Institute

JOL

ICTR

Life Science Research Network Wales

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference38 articles.

1. Itraconazole inhibits angiogenesis and tumor growth in non-small cell lung cancer;Aftab;Canc. Res.,2011

2. Broad-range inhibition of enterovirus replication by OSW-1, a natural compound targeting OSBP;Albulescu;Antivir. Res.,2015

3. Repurposing itraconazole as a treatment for advanced prostate cancer: a noncomparative randomized phase II trial in men with metastatic castration-resistant prostate cancer;Antonarakis;Oncol.,2013

4. Oxysterol-binding protein family I is the target of minor enviroxime-like compounds;Arita;J. Virol.,2013

5. Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer;Bassetto;Eur. J. Med. Chem.,2016

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