An acyclic phosphonate prodrug of HPMPC is effective against VZV in skin organ culture and mice-Reference-Cited by-同舟云学术

An acyclic phosphonate prodrug of HPMPC is effective against VZV in skin organ culture and mice

Published:2022-03 Issue: Volume:199 Page:105275
ISSN:0166-3542
Container-title:Antiviral Research
language:en
Short-container-title:Antiviral Research

Author:

Lloyd M.G.,Liu D.,Lyu J.,Fan J.,Overhulse J.M.,Kashemirov B.A.,Prichard M.N.,McKenna C.E.,Moffat J.F.^ORCID

Publisher

Elsevier BV

Subject

Virology,Pharmacology

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4. beta-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism;De;Antivir. Res.,2014

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