High throughput profiling identified PA-L106R amino acid substitution in A(H1N1)pdm09 influenza virus that confers reduced susceptibility to baloxavir in vitro

Author:

Chen DongdongORCID,Su WenORCID,Choy Ka-Tim,Chu Yan Sing,Lin Chi Ho,Yen Hui-LingORCID

Funder

Research Grants Council, University Grants Committee

Health and Medical Research Fund

Publisher

Elsevier BV

Reference41 articles.

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2. The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit;Dias;Nature,2009

3. Mapping the evolutionary potential of RNA viruses;Dolan;Cell Host Microbe,2018

4. Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase. Proceedings of the Japan Academy;Furuta;Series B, Physical and biological sciences,2017

5. Global update on the susceptibilities of human influenza viruses to neuraminidase inhibitors and the cap-dependent endonuclease inhibitor baloxavir, 2018-2020;Govorkova;Antivir. Res.,2022

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