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Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt

  • Published:2005-12-22 Issue:2 Volume:580 Page:703-710
  • ISSN:0014-5793
  • Container-title:FEBS Letters
  • language:en
  • Short-container-title:

Author:

Biswas Kamal Krishna,Tancharon Salunya,Sarker Krishna Pada,Kawahara Ko-ichi,Hashiguchi Teruto,Maruyama Ikuro

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Reference44 articles.

1. Synthesis of di-cepharanthine;Tomita;Tetrahedron Lett.,1967

2. Potentiation of antitumor activity of vincristine by biscoclaurine alkaloid cepharanthine;Kato;J. Natl. Cancer Inst.,1987

3. Suppression of cytokine production and neural cell death by the anti-inflammatory alkaloid cepharanthine: a potential agent against HIV-1 encephalopathy;Okamoto;Biochem. Pharmacol.,2001

4. The prevention of lipopolysaccharide-induced pulmonary vascular injury by pretreatment with cepharanthine in rats;Murakami;Am. J. Respir. Crit. Care Med.,2000

5. Cepharanthine (biscoclaurine alkaloid) treatment in endotoxic shock of suckling rats;Goto;J. Pharm. Pharmacol.,1991
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