Alcynyl-5 desoxy-2′ uridines par couplages d'organozinciques acetyleniques avec l'iodo-s 0-3′, 5′-bis(trimethylsilyl) desoxyuridine, catalyses par des complexes organopalladies et de nickel
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference15 articles.
1. Nucleoside analogs with antiviral activity
2. SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME NOVEL ANALOGS OF THYMIDINE
3. Synthesis of 1-(2-deoxy-β--pentofuranosyl)-5-ethylnyl-1,2,3,4,-tetrahydropyrimidine-2,4-dione (5-ethynyl-2′-deoxyuridine)
4. Antiviral Action and Cellular Toxicity of Four Thymidine Analogues: 5-Ethyl-, 5-Vinyl-, 5-Propyl-, and 5-Allyl-2′-Deoxyuridine
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1. Inhibition of Mycobacterial Replication by Pyrimidines Possessing Various C-5 Functionalities and Related 2′-Deoxynucleoside Analogues Using in Vitro and in Vivo Models;Journal of Medicinal Chemistry;2010-07-22
2. Synthesis of 5-Fluoroalkylated Pyrimidine Nucleosides via Negishi Cross-Coupling;The Journal of Organic Chemistry;2008-06-04
3. Growth Inhibition of Mycobacterium bovis, Mycobacterium tuberculosis and Mycobacterium avium In Vitro: Effect of 1-β-d-2‘-Arabinofuranosyl and 1-(2‘-Deoxy-2‘-fluoro-β-d-2‘-ribofuranosyl) Pyrimidine Nucleoside Analogs;Journal of Medicinal Chemistry;2007-06-29
4. 5-Alkynyl-2′-deoxyuridines: Chromatography-free synthesis and cytotoxicity evaluation against human breast cancer cells;Bioorganic & Medicinal Chemistry;2007-04
5. Design and Studies of Novel 5-Substituted Alkynylpyrimidine Nucleosides as Potent Inhibitors of Mycobacteria;Journal of Medicinal Chemistry;2005-10-01
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