Structure-Guided Identification of Resistance Breaking Antimalarial N‑Myristoyltransferase Inhibitors-Reference-Cited by-同舟云学术

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Structure-Guided Identification of Resistance Breaking Antimalarial N‑Myristoyltransferase Inhibitors

Published:2019-07 Issue:7 Volume:26 Page:991-1000.e7
ISSN:2451-9456
Container-title:Cell Chemical Biology
language:en
Short-container-title:Cell Chemical Biology

Author:

Schlott Anja C.^ORCID,Mayclin Stephen^ORCID,Reers Alexandra R.^ORCID,Coburn-Flynn Olivia,Bell Andrew S.^ORCID,Green Judith^ORCID,Knuepfer Ellen^ORCID,Charter David,Bonnert Roger^ORCID,Campo Brice^ORCID,Burrows Jeremy^ORCID,Lyons-Abbott Sally,Staker Bart L.^ORCID,Chung Chun-Wa^ORCID,Myler Peter J.^ORCID,Fidock David A.^ORCID,Tate Edward W.^ORCID,Holder Anthony A.^ORCID

Funder

Francis Crick Institute

Cancer Research UK

Medical Research Council

Wellcome Trust

SPR

Seattle Structural Genomics Center for Infectious Disease

Department of Health and Human Services

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry

Reference57 articles.

1. PHENIX: a comprehensive Python-based system for macromolecular structure solution;Adams;Acta Crystallogr. D Biol. Crystallogr.,2010

2. A molecular marker of artemisinin-resistant Plasmodium falciparum malaria;Ariey;Nature,2014

3. Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs;Bell;PLoS Negl. Trop. Dis.,2012

4. Diverse modes of binding in structures of Leishmania major N-myristoyltransferase with selective inhibitors;Brannigan;IUCrJ,2014

5. N-Myristoyltransferase from Leishmania donovani: structural and functional characterisation of a potential drug target for visceral leishmaniasis;Brannigan;J. Mol. Biol.,2010

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1. ResMAP—a saturation mutagenesis platform enabling parallel profiling of target-specific resistance-conferring mutations in Plasmodium;mBio;2024-08-27

2. Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms;Structure;2024-08

3. Post-Translational Modifications of Proteins of Malaria Parasites during the Life Cycle;International Journal of Molecular Sciences;2024-06-02

4. Antimalarial Drug Discovery from Natural and Synthetic Sources;Current Medicinal Chemistry;2024-05-30

5. Exploring Subsite Selectivity within Plasmodium vivax N-Myristoyltransferase Using Pyrazole-Derived Inhibitors;Journal of Medicinal Chemistry;2024-04-29

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