Probing the Coagulation Pathway with Aptamers Identifies Combinations that Synergistically Inhibit Blood Clot Formation

Author:

Bompiani Kristin M.,Lohrmann Jens L.,Pitoc George A.,Frederiksen James W.,Mackensen George B.,Sullenger Bruce A.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

Reference40 articles.

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3. Synergy, additivism and antagonism in immunosuppression. A critical review;Berenbaum;Clin. Exp. Immunol.,1977

4. Mechanisms of thrombin generation during surgery and cardiopulmonary bypass;Boisclair;Blood,1993

5. A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity;Bompiani;J. Thromb. Haemost.,2012

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