Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples
Author:
Funder
National Institutes of Health
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry
Reference61 articles.
1. GROMACS: high performance molecular simulations through multi-level parallelism from laptops to supercomputers;Abraham;SoftwareX,2015
2. The discovery of Mary's mutation;Asselta;J. Thromb. Haemost.,2003
3. Nucleic acid aptamers as antithrombotic agents: opportunities in extracellular therapeutics;Becker;Thromb. Haemost.,2010
4. Mutation in blood coagulation factor V associated with resistance to activated protein C;Bertina;Nature,1994
5. Selection of single-stranded DNA molecules that bind and inhibit human thrombin;Bock;Nature,1992
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