Leinamycin Biosynthesis Revealing Unprecedented Architectural Complexity for a Hybrid Polyketide Synthase and Nonribosomal Peptide Synthetase
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry
Reference60 articles.
1. Leinamycin, a new antitumor antibiotic from Streptomyces;Hara;J. Antibiot. (Tokyo),1989
2. DC 107, a novel antitumor antibiotic produced by a Streptomyces sp;Hara;J. Antibiot. (Tokyo),1989
3. Mechanism based screens for natural products leads as sources for antitumor drugs;Nakano,1992
4. DNA strand scission by the novel antitumor antibiotic leinamycin;Hara;Biochemistry,1990
5. Thiol-mediated DNA alkylation by the novel antitumor antibiotic leinamycin;Asai;J. Am. Chem. Soc.,1996
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