TINS, Target Immobilized NMR Screening: An Efficient and Sensitive Method for Ligand Discovery-Reference-Cited by-同舟云学术

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TINS, Target Immobilized NMR Screening: An Efficient and Sensitive Method for Ligand Discovery

Published:2005-02 Issue:2 Volume:12 Page:207-216
ISSN:1074-5521
Container-title:Chemistry & Biology
language:en
Short-container-title:Chemistry & Biology

Author:

Vanwetswinkel Sophie,Heetebrij Robert J.,van Duynhoven John,Hollander Johan G.,Filippov Dmitri V.,Hajduk Philip J.,Siegal Gregg

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

Reference34 articles.

1. Is there a difference between leads and drugs? A historical perspective;Oprea;J. Chem. Inf. Comput. Sci.,2001

2. The design of leadlike combinatorial libraries;Teague;Angew. Chem. Int. Ed. Engl.,1999

3. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings;Lipinski;Adv. Drug Deliv. Rev.,1997

4. Discovering high-affinity ligands for proteins: SAR by NMR;Shuker;Science,1996

5. Drug design: Discovering high-affinity ligands for proteins;Hajduk;Science,1997

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