Driving CARs on the uneven road of antigen heterogeneity in solid tumors-Reference-Cited by-同舟云学术

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Driving CARs on the uneven road of antigen heterogeneity in solid tumors

Published:2018-04 Issue: Volume:51 Page:103-110
ISSN:0952-7915
Container-title:Current Opinion in Immunology
language:en
Short-container-title:Current Opinion in Immunology

Author:

Chen Nan,Li Xiaoyu,Chintala Navin K,Tano Zachary E,Adusumilli Prasad S

Funder

National Institutes of Health

U.S. Department of Defense

Derfner Foundation

Joanne and John DallePezze Foundation

Commonwealth Foundation for Cancer Research

Experimental Therapeutics Center of Memorial Sloan Kettering Cancer Center

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference54 articles.

1. The basic principles of chimeric antigen receptor design;Sadelain;Cancer Discov,2013

2. The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity;Thistlethwaite;Cancer Immunol Immunother,2017

3. Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication;Zhong;Mol Ther,2010

4. Inhibition of TGF-beta signaling in genetically engineered tumor antigen-reactive T cells significantly enhances tumor treatment efficacy;Zhang;Gene Ther,2013

5. Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition;Cherkassky;J Clin Invest,2016

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