Chimeric Antigen Receptors Combining 4-1BB and CD28 Signaling Domains Augment PI3kinase/AKT/Bcl-XL Activation and CD8+ T Cell–mediated Tumor Eradication
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine
Reference50 articles.
1. Induction of antigen-specific T cell anergy: An early event in the course of tumor progression;Staveley-O'Carroll;Proc Natl Acad Sci USA,1998
2. T cell anergy;Schwartz;Annu Rev Immunol,2003
3. Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells;Townsend;Science,1993
4. Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway;Melero;Eur J Immunol,1998
5. Engagement of the OX-40 receptor in vivo enhances antitumor immunity;Weinberg;J Immunol,2000
Cited by 439 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Suppressive immune microenvironment and CART therapy for glioblastoma: Future prospects and challenges;Cancer Letters;2024-09
2. Molecular mechanism of co-stimulatory domains in promoting CAR-T cell anti-tumor efficacy;Biochemical Pharmacology;2024-09
3. Artificial antigen-presenting cells: the booster for the obtaining of functional adoptive cells;Cellular and Molecular Life Sciences;2024-08-31
4. Third-generation anti-CD19 CAR T cells for relapsed/refractory chronic lymphocytic leukemia: a phase 1/2 study;Leukemia;2024-08-27
5. Novel immunotherapeutics against LGR5 to target multiple cancer types;EMBO Molecular Medicine;2024-08-21
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3