Ultra-sensitive detection of microRNA-21 based on duplex-specific nuclease-assisted target recycling and horseradish peroxidase cascading signal amplification

Author:

Peng Weipan,Zhao Qian,Piao Jiafang,Zhao Miao,Huang Yiwen,Zhang Bo,Gao Weichen,Zhou Dianming,Shu Guiming,Gong XiaoqunORCID,Chang Jin

Funder

National Natural Science Foundation of China

Tianjin Natural Science Foundation

key technologies R&D program of Tianjin

Seed Foundation of Tianjin University

Publisher

Elsevier BV

Subject

Materials Chemistry,Electrical and Electronic Engineering,Metals and Alloys,Surfaces, Coatings and Films,Condensed Matter Physics,Instrumentation,Electronic, Optical and Magnetic Materials

Reference32 articles.

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2. Isolation, characterization and molecular cloning of duplex-specific nuclease from the hepatopancreas of the Kamchatka crab;Anisimova;BMC Biochem.,2008

3. An integrated dual functional recognition/amplification bio-label for the one-step impedimetric detection of Micro-RNA-21;Azzouzi;Biosens. Bioelectron.,2017

4. Bias in high-throughput analysis of miRNAs and implications for biomarker studies;Backes;Anal. Chem.,2016

5. MicroRNA profiling: separating signal from noise;Baker;Nat. Methods,2010

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