Genotypic characterization of ‘inferred’ rifampin mutations in GenoType MTBDRplus assay and its association with phenotypic susceptibility testing of Mycobacterium tuberculosis.

Author:

Singhal Ritu,Anthwal Divya,Kumar Gavish,Sah Grish,Salfinger Max,Choudhury Sangeeta,Arora Jyoti,Bhalla Manpreet,Myneedu Vithal P.,Sarin Rohit,Haldar Sagarika

Funder

Department of Science and Technology

Translational Health Science and Technology Institute

Department of Biotechnology

Ministry of Science and Technology

Publisher

Elsevier BV

Subject

Infectious Diseases,Microbiology (medical),General Medicine

Reference40 articles.

1. Abanda NN, Djieugoue JY, Khadka VS, Pefura-Yone EW, Mbacham WF, Vernet G, et al. Absence of hybridization with the wild-type and mutant rpoB probes in the Genotype MTBDRplus assay detects 'disputed' rifampicin mutations. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2017. Epub 2017/12/09. doi: 10.1016/j.cmi.2017.11.021. PubMed PMID: 29217277.

2. Rifampin drug resistance tests for tuberculosis: challenging the gold standard;Armand Van Deun;Journal of clinical microbiology.,2013

3. Bai Y, Wang Y, Shao C, Hao Y, Jin Y. GenoType MTBDRplus assay for rapid detection of multidrug resistance in mycobacterium tuberculosis: a meta-analysis. PloS one. 2016;11(3):e0150321. Epub 2016/03/05. doi: https://doi.org/10.1371/journal.pone.0150321. PubMed PMID: 26934724; PubMed Central PMCID: PMC4774872.

4. Bartfai Z, Somoskovi A, Kodmon C, Szabo N, Puskas E, Kosztolanyi L, et al. Molecular characterization of rifampin-resistant isolates of Mycobacterium tuberculosis from Hungary by DNA sequencing and the line probe assay. Journal of clinical microbiology. 2001;39(10):3736-9. Epub 2001/09/28. doi: 10.1128/JCM.39.10.3736-3739.2001. PubMed PMID: 11574605; PubMed Central PMCID: PMCPMC88421.

5. Brandis G, Hughes D. Mechanisms of fitness cost reduction for rifampicin-resistant strains with deletion or duplication mutations in rpoB. Scientific reports. 2018;8(1):17488. Epub 2018/12/07. doi: 10.1038/s41598-018-36005-y. PubMed PMID: 30504835; PubMed Central PMCID: PMCPMC6269455.

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