Development of a solvate as an active pharmaceutical ingredient: Developability, crystallisation and isolation challenges

Author:

Douillet Julien,Stevenson Neil,Lee Mei,Mallet Franck,Ward Richard,Aspin Peter,Dennehy Daniel Robert,Camus Laure

Publisher

Elsevier BV

Subject

Materials Chemistry,Inorganic Chemistry,Condensed Matter Physics

Reference17 articles.

1. The importance of solvates;Griesser,2006

2. Characterization of habits and crystalline modification of solids and their pharmaceutical applications;Haleblian;J. Pharm. Sci.,1975

3. H.G. Brittain, D.J.W. Grant, Effects of polymorphism and solid-state solvation on solubility and dissolution rate, in: H.G. Brittain (Ed.), Polymorphism in Pharmaceutical Solids, Vol. 95. Drugs and the Pharmaceutical Sciences, US, 1999, pp. 279–330.

4. Dissolution rate of polymorphs and two new pseudopolymorphs of sulindac;Tros de Ilarduya;Drug Dev. Ind. Pharm.,1997

5. Expanding the scope of crystal form evaluation in pharmaceutical science;Peterson;J. Pharm. Pharm. Sci.,2006

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