Poly(2-oxazoline) nanoparticle delivery enhances the therapeutic potential of vismodegib for medulloblastoma by improving CNS pharmacokinetics and reducing systemic toxicity-Reference-Cited by-同舟云学术

Poly(2-oxazoline) nanoparticle delivery enhances the therapeutic potential of vismodegib for medulloblastoma by improving CNS pharmacokinetics and reducing systemic toxicity

Published:2021-02 Issue: Volume:32 Page:102345
ISSN:1549-9634
Container-title:Nanomedicine: Nanotechnology, Biology and Medicine
language:en
Short-container-title:Nanomedicine: Nanotechnology, Biology and Medicine

Author:

Hwang Duhyeong,Dismuke Taylor,Tikunov Andrey,Rosen Elias P.,Kagel John R.,Ramsey Jacob D.,Lim Chaemin,Zamboni William,Kabanov Alexander V.,Gershon Timothy R.,Sokolsky-Papkov PhD Marina

Funder

National Institutes of Health

St. Baldrick's Foundation

Publisher

Elsevier BV

Subject

Pharmaceutical Science,General Materials Science,Biomedical Engineering,Molecular Medicine,Medicine (miscellaneous),Bioengineering

Reference48 articles.

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3. Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma;Yauch;Science,2009

4. Single and multiple dose intravenous and oral pharmacokinetics of the hedgehog pathway inhibitor vismodegib in healthy female subjects;Graham;Br J Clin Pharmacol,2012

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