Effects of PTEN inhibition on regulation of tau phosphorylation in an okadaic acid‐induced neurodegeneration model
Author:
Affiliation:
1. Department of PharmacologyCollege of Pharmacy, 88 Jiao‐Tong RoadFujian Medical UniversityFuzhou350004FujianPR China
Funder
Natural Science Foundation of Fujian Province
Publisher
Wiley
Subject
Developmental Biology,Developmental Neuroscience
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1016/j.ijdevneu.2012.08.003
Reference56 articles.
1. Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5
2. Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules
3. Okadaic Acid Induces Early Changes in Microtubule-Associated Protein 2 and γ Phosphorylation Prior to Neurodegeneration in Cultured Cortical Neurons
4. Role of Tau Protein in Both Physiological and Pathological Conditions
5. PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations
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