Asymmetric bioreduction of (2-(4-nitro-phenyl)-N-(2-oxo-2-pyridin-3-yl-ethyl)-acetamide) to its corresponding (R) alcohol [(R)-N- (2-hydroxy-2-pyridin-3-yl-ethyl)-2-(4-nitro-phenyl)-acetamide] by using Candida sorbophila MY 1833

Author:

Chartrain Michel,Roberge Christopher,Chung John,McNamara James,Zhao Dalian,Olewinski Roger,Hunt George,Salmon Peter,Roush David,Yamazaki Shigeko,Wang Tao,Grabowski Edward,Buckland Barry,Greasham Randolph

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,Biochemistry,Biotechnology,Bioengineering

Reference22 articles.

1. Nonchiral, homochiral and composite chiral drugs;Ariens;TIBS,1993

2. Current regulatory (draft) guidance on chiral medicinal products;Rauws;Chirality,1994

3. Stinson S. Chiral drugs. C&EN 1994:9;38–72.

4. Enzymes in organic synthesis;Jones;Tetrahedron,1986

5. Biotransformations of industrial use;Kieslich;Acta Biotechnol,1991

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