Phosphine Effects in the Copper(I) Hydride-Catalyzed Hydrogenation of Ketones and Regioselective 1,2-Reduction of α,β-Unsaturated Ketones and Aldehydes. Hydrogenation of Decalin and Steroidal Ketones and Enones

Author:

Chen Jian-Xin,Daeuble John F.,Stryker Jeffrey M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference39 articles.

1. (a) Daeuble, J. F., Stryker, J. M. Catalysis of Organic Reactions; Scaros, M. G., Prunier, M. L., Eds.; Marcel Dekker: New York, 1995; pp 235–247 (Chem. Ind. 1995, 62).

2. (b) Chen, J.-X.; Daeuble, J. F.; Brestensky, D. M.; Stryker, J. M. Tetrahedron (Symposium-in-Print, ‘Transition Metal Organometallics in Organic Synthesis’) 2000, 56, 2153–2166.

3. The ruthenium hydrogenation catalyst reported by Noyori et al., is also selective for the 1,2-reduction of unsaturated carbonyl compounds, including asymmetric hydrogenation: Ohkuma, T.; Ooka, H.; Ikariya, T.; Noyori, R. J. Am. Chem. Soc. 1995, 117, 10417.

4. For references to other catalysts for the chemoselective hydrogenation and hydrosilylation of unsaturated carbonyl compounds, see the citations provided in Ref. 1b.

5. (a) Mahoney, W. S.; Stryker, J. M. J. Am. Chem. Soc. 1989, 111, 8818.

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