Affiliation:
1. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Abstract
Copper hydride catalysis was used for selective N,O-reduction of 2,1-benzoisoxazoles in continuous flow to access 2-aminobenzophenones, key intermediates and cost drivers in the synthesis of benzodiazepines.
Funder
Virginia Commonwealth University
Publisher
Royal Society of Chemistry (RSC)
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