Generation of Cyclopenta[c]piperidines and Pyrrolo[3,4-c]piperidines—Potential Substance P Antagonists—from Adducts of Cyclic Dienophiles and 5-Chloro-6-methyl-3-phenyl-2H-1,4-oxazin-2-one-Reference-Cited by-同舟云学术

Generation of Cyclopenta[c]piperidines and Pyrrolo[3,4-c]piperidines—Potential Substance P Antagonists—from Adducts of Cyclic Dienophiles and 5-Chloro-6-methyl-3-phenyl-2H-1,4-oxazin-2-one

Published:2000-08 Issue:34 Volume:56 Page:6279-6290
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Wu Xiujuan,Toppet Suzanne,Compernolle Frans,Hoornaert Georges J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference32 articles.

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2. (b) Swain, C. Exp. Opin. Ther. Patents 1996, 6, 367–378 and references cited therein.

3. (c) Kramer, M. S.; Cutler, N. et al. Science 1998, 281, 1640–1645.

4. A Potent Nonpeptide Antagonist of the Substance P (NK 1 ) Receptor

5. Discovery of a potent substance P antagonist: recognition of the key molecular determinant

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