A Potent Nonpeptide Antagonist of the Substance P (NK 1 ) Receptor
Author:
Affiliation:
1. Department of Exploratory Medicinal Chemistry, Central Research Division, Pfizer Inc., Groton, CT 06340.
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Multidisciplinary
Reference29 articles.
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2. BUCK, S.H., THE TACHYKININS - A FAMILY OF PEPTIDES WITH A BROOD OF RECEPTORS, TRENDS IN PHARMACOLOGICAL SCIENCES 7: 65 (1986).
3. CHANG, M.M., ISOLATION OF A SIALOGOGIC PEPTIDE FROM BOVINE HYPOTHALAMIC TISSUE AND ITS CHARACTERIZATION AS SUBSTANCE-P, JOURNAL OF BIOLOGICAL CHEMISTRY 245: 4784 (1970).
4. CHENG, Y, RELATIONSHIP BETWEEN INHIBITION CONSTANT (K1) AND CONCENTRATION OF INHIBITOR WHICH CAUSES 50 PER CENT INHIBITION (I50) OF AN ENZYMATIC-REACTION, BIOCHEMICAL PHARMACOLOGY 22: 3099 (1973).
5. Constantine, J. W., Naunyn-Schmiedeberg's Archives of Pharmacology 344: 471 (1991).
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