Practical synthesis of acetophenones from phenoltriflates
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference13 articles.
1. (a) Tanaka, A.; Terasawa, T.; Hagihara, H.; Sakuma, Y.; Ishibe, N.; Sawada, M.; Takasugi, H.; Tanaka, H. J. Med. Chem. 1998, 41, 2390–2410;
2. (b) Astles, P. C.; Brealey, C.; Brown, T. J.; Facchini, V.; Handscombe, C.; Harris, N. V.; McCarthy, C.; McLay, I. M.; Porter, B.; Roach, A. G.; Sargent, C.; Smith, C.; Walsh, R. J. A. J. Med. Chem. 1998, 41, 2732–2744.
3. Renault, O.; Dallemagne, P.; Rault, S. Org. Prep. Proced. Int. 1999, 31, 324–328 and references cited therein.
4. Acylation of 2-chlorotoluene according to: Man, E. H.; Hauser, C. R. J. Org. Chem. 1952, 17, 397–403 gave a quantitative yield of an 80/20 mixture of non-separable 4-chloro-3-methylacetophenone and 3-chloro-4-methylacetophenone, respectively.
5. (a) Cabri, W.; Candiani, I.; Bedeschi, A.; Santi, R. J. Org. Chem. 1990, 55, 3654–3655;
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