Selective Endothelin A Receptor Antagonists. 3. Discovery and Structure−Activity Relationships of a Series of 4-Phenoxybutanoic Acid Derivatives-Reference-Cited by-同舟云学术

Selective Endothelin A Receptor Antagonists. 3. Discovery and Structure−Activity Relationships of a Series of 4-Phenoxybutanoic Acid Derivatives

Published:1998-06-20 Issue:15 Volume:41 Page:2732-2744
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Astles Peter C.¹,Brealey Clive¹,Brown Thomas J.¹,Facchini Vincenzo¹,Handscombe Caroline¹,Harris Neil V.¹,McCarthy Clive¹,McLay Iain M.¹,Porter Barry¹,Roach Alan G.¹,Sargent Carol¹,Smith Christopher¹,Walsh Roger J. A.¹

Affiliation:

1. Rhône-Poulenc Rorer, Dagenham Research Centre, Rainham Road South, Dagenham, Essex RM10 7XS, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9707131

Reference31 articles.

1. A novel potent vasoconstrictor peptide produced by vascular endothelial cells

2. Growth regulatory properties of endothelins

3. Presence of non-selective type of endothelin receptor on vascular endothelium and its linkage to vasodilation

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