New synthesis of 5-amino-4-hydroxy-2,6-dimethylheptanoic acid, a hydroxyethylene isostere of the Val-Ala dipeptide
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
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5. Dreyer, G. B.; Lambert, D. M.; Meek, T. D.; Carr, T. J.; Tomaszek Jr., T. A.; Fernandez, A. V.; Bartus, H.; Cacciavillani, E.; Hassell, A. M.; Minnich, M.; Petteway Jr., S. R.; Metcalf, B. W.; Lewis, M. Biochemistry 1992, 31, 6646–6659.
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1. Synthesis of β‐Secretase Inhibitors Containing a Hydroxyethylene Dipeptide Isostere;Synthetic Communications;2007-01-01
2. Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors;Bioorganic & Medicinal Chemistry Letters;2006-09
3. The synthesis of N -acyl-2-hydroxymethyl aziridines of biological interest;Tetrahedron Letters;2004-02
4. Val-Ala Dipeptide Isosteres by Hydrocyanation of α′-Amino α,β-Unsaturated Ketones − Control of Stereoselectivity by the N-Protecting Group;European Journal of Organic Chemistry;2003-05
5. One-Step Highly Diastereoselective Synthesis of γ-Aminoalkyl-Substituted γ-Butyrolactones by an Asymmetric Samarium-Mediated Ketyl−Alkene Coupling Reaction;The Journal of Organic Chemistry;2003-02-04
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