Synthesis of β‐Secretase Inhibitors Containing a Hydroxyethylene Dipeptide Isostere-Reference-Cited by-同舟云学术

Synthesis of β‐Secretase Inhibitors Containing a Hydroxyethylene Dipeptide Isostere

Published:2007-01-01 Issue:1 Volume:37 Page:9-24
ISSN:0039-7911
Container-title:Synthetic Communications
language:en
Short-container-title:Synthetic Communications

Author:

Yang Xiaoming¹,Zou Xiaomin¹,Fu Yiqiu¹,Mou Ke¹,Fu Gang¹,Ma Chao¹,Xu Ping¹

Affiliation:

1. a Department of Medicinal Chemistry , School of Pharmaceutical Sciences, State Key Laboratory of Natural and Biomimetic Drugs, Peking University , Beijing, China

Publisher

Informa UK Limited

Subject

Organic Chemistry

Link

https://www.tandfonline.com/doi/pdf/10.1080/00397910600977509

Reference24 articles.

1. Secretases as targets for the treatment of Alzheimer’s disease

2. Biogenesis and metabolism of Alzheimer’s disease Aβ amyloid peptides

3. Structure-Based Design: Potent Inhibitors of Human Brain Memapsin 2 (β-Secretase)

4. β-Secretase as a Therapeutic Target for Inhibitor Drugs

5. Synthesis of potent β-secretase inhibitors containing a hydroxyethylamine dipeptide isostere and their structure–activity relationship studies

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Stereoselective Barbier-Type Allylations and Propargylations Mediated by CpTiCl3;The Journal of Organic Chemistry;2018-12-24

2. Synthesis and biological evaluation of quinazolinone-based hydrazones with potential use in Alzheimer’s disease;Bioorganic Chemistry;2017-10

3. Enantioselective synthesis of the side-chain acid of homoharringtonine and harringtonine from the same γ-butyrolactone intermediate;Arkivoc;2016-06-01

4. An Alternative Synthetic Route to (3R,5S,1′S)-5-{1′-[(tert-Butyloxycarbonyl)amino]-3′-methylbutyl}-3-methyldihydrofuran-2(3H)-one, a Precursor of a Leu-Ala Hydroxyethylene Isostere;Synthesis;2015-07-21

5. A two-step synthesis of the bioprotective agent JP4-039 from N-Boc-l-leucinal;Tetrahedron;2014-05