High isolated yields in thermolysin-catalysed synthesis of Z-l-aspartyl-l-phenylalanine methyl ester in toluene at controlled water activity
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference20 articles.
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2. Synthesis of dipeptide precursors with an immobilized thermolysin in ethyl acetate
3. Oyama, K.; Irino, S.; Hagi, N. In Methods in Enzymology; Colowick, S. P.; Kaplan, N. O., Eds. Production of Aspartame by Immobilized Thermoase. Academic Press: San Diego, 1987; Vol. 136, pp. 503–516.
4. On the mechanism of the action of thermolysin: kinetic study of the thermolysin-catalysed condensation reaction of N-benzyloxycarbonyl-L-aspartic acid with L-phenylalanine methyl ester
5. The thermolysin-catalyzed condensation reactions of n-substituted aspartic and glutamic acids with phenylalanine alkyl esters
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