Nucleophilic addition of methyllithium to chiral oxime ethers: asymmetric preparation of 1-(aryl)ethylamines and application to a synthesis of calcimimetics (+)-NPS R-568 and its thio analogue
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference22 articles.
1. Additions of Organometallic Reagents to CN Bonds: Reactivity and Selectivity
2. Diastereofacial Discrimination in the Reaction of Chiral Alkoxymethyl Oxime Ethers with Allyl Metallic Reagents
3. Addition of aryllithium compounds to oxime ethers
4. Chiral oximes in asymmetric synthesis. Addition of organometallic reagents to o-(1-phenylethyl) aldoximes
5. Addition of Organolithiums to the (R)-O-(1-Phenylbutyl)hydroxylamine (ROPHy) Oxime of Cinnamaldehyde. Asymmetric Synthesis of α-Aminoacids
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