Transaminase-mediated chiral selective synthesis of (1R)-(3-methylphenyl)ethan-1-amine from 1-(3-methylphenyl)ethan-1-one: process minutiae, optimization, characterization and ‘What If studies’
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Bioengineering,Biotechnology
Link
https://link.springer.com/content/pdf/10.1007/s00449-022-02824-7.pdf
Reference54 articles.
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2. Yamazaki N, Atobe M, Kibayashi C (2001) Nucleophilic addition of methyllithium to chiral oxime ethers: asymmetric preparation of 1-(aryl) ethylamines and application to a synthesis of calcimimetics (+)-NPS R-568 and its thio analogue. Tetrahedron Lett 42(30):5029–5032. https://doi.org/10.1016/S0040-4039(01)00910-8
3. Han R, Cao X, Fang H, Zhou J, Ni Y (2021) Structure-based engineering of ω-transaminase for enhanced catalytic efficiency toward (R)-(+)-1-(1-naphthyl) ethylamine synthesis. Mol Catal 502:111368. https://doi.org/10.1016/j.mcat.2020.111368
4. Fuchs M, Koszelewski D, Tauber K, Sattler J, Banko W, Holzer AK, Pickl M, Kroutil W, Faber K (2012) Improved chemoenzymatic asymmetric synthesis of (S)-Rivastigmine. Tetrahedron 68(37):7691–7694. https://doi.org/10.1016/j.tet.2012.06.031
5. Pallavicini M, Valoti E, Villa L, Piccolo O (2001) Resolution of ortho-and meta-substituted 1-phenylethylamines with isopropylidene glycerol hydrogen phthalate. Tetrahedron Asymmetry 12(7):1071–1075. https://doi.org/10.1016/S0957-4166(01)00156-2
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