Synthesis of a potent β-lactamase inhibitor- 1,1-dioxo-6-(2-pyridyl)methylenepenicillanic acid and its reaction with sodium methoxide
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference27 articles.
1. Clavulanic acid, a novel β-lactam isolated from Streptomyces clavuligerus; X-ray crystal structure analysis
2. CP-45,899, a Beta-Lactamase Inhibitor That Extends the Antibacterial Spectrum of Beta-Lactams: Initial Bacteriological Characterization
3. 6-beta-bromopenicillanic acid, a potent beta-lactamase inhibitor.
4. 6 β-Bromopenicillanic acid inactivates β-lactamase I
5. 6-Acetylmethylenepenicillanic acid (Ro 15-1903), a potent .BETA.-lactamase inhibitor. I. Inhibition of chromosomally and R-factor-mediated .BETA.-lactamases.
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