Modified oligonucleotides: IV solid phase synthesis and preliminary evaluation of phosphorothioate RNA as potential antisense agents.
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference15 articles.
1. Oligodeoxynucleotides,- Antisense Inhibitors of Gene Expression;Mc Millan Topics in Strutural Biology Series,1989
2. Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells.
3. Sugar modified oligonucleotides : II. Solid phase synthesis of nuclease resistant α-anomeric uridylates as potential antisense agents
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1. Automated Solid-Phase Synthesis of RNA Oligonucleotides Containing a Nonbridging Phosphorodithioate Linkage via Phosphorothioamidites;The Journal of Organic Chemistry;2012-10-25
2. 3H-1,2-Benzodithiol-3-one 1,1-dioxide;Encyclopedia of Reagents for Organic Synthesis;2012-09-14
3. Characterisation of a modified oligonucleotide together with its synthetic impurities using accurate mass measurements;Rapid Communications in Mass Spectrometry;2011-01-17
4. Development of siRNA for therapeutics: Efficient synthesis of phosphorothioate RNA utilizing phenylacetyl disulfide (PADS);Bioorganic & Medicinal Chemistry Letters;2006-05
5. 3H-1,2-Benzodithiol-3-one 1,1-Dioxide;Encyclopedia of Reagents for Organic Synthesis;2002-10-15
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