Development of siRNA for therapeutics: Efficient synthesis of phosphorothioate RNA utilizing phenylacetyl disulfide (PADS)-Reference-Cited by-同舟云学术

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Development of siRNA for therapeutics: Efficient synthesis of phosphorothioate RNA utilizing phenylacetyl disulfide (PADS)

Published:2006-05 Issue:9 Volume:16 Page:2513-2517
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ravikumar Vasulinga T.,Andrade Mark,Carty Recaldo L.,Dan Amy,Barone Steve

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference43 articles.

1. Molecular mechanisms of action of antisense drugs

3. RNA interference is mediated by 21- and 22-nucleotide RNAs

4. RNA interference and chemically modified small interfering RNAs

5. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

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1. Antisense oligonucleotide–mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice;Journal of Lipid Research;2021

2. Role of a ribosomal RNA phosphate oxygen during the EF-G–triggered GTP hydrolysis;Proceedings of the National Academy of Sciences;2015-05-04

3. Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr-/- mice;Journal of Lipid Research;2013-10

4. Convenient synthesis of nucleoside 5′-(α-P-thio)triphosphates and phosphorothioate nucleic acids (DNA and RNA);Science China Chemistry;2011-11-28

5. Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes;Nucleic Acids Research;2011-02-23

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