Total Synthesis of (±)-Barbatusol

Author:

Koft Emil R.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference20 articles.

1. Isolation, structure determination, and absolute configuration of barbatusol, a new bioactive diterpene with a rearranged abietane skeleton from the labiate coleus barbatus

2. a) Previous synthetic work: a)For the preparation of 1a as a mixture of double bond isomers from carnosol, see ref. 1.

3. Total synthesis of ± pisiferin (11-deshydroxy barbutusol);Matsumoto;Bull. Chem. Soc. Japan,1986

4. Conversion of pisiferin to1a;Hasegawa;Chem. Lett.,1984

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