Detecting low-level synthesis impurities in modified phosphorothioate oligonucleotides using liquid chromatography–high resolution mass spectrometry-Reference-Cited by-同舟云学术

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Detecting low-level synthesis impurities in modified phosphorothioate oligonucleotides using liquid chromatography–high resolution mass spectrometry

Published:2011-07 Issue:2-3 Volume:304 Page:98-104
ISSN:1387-3806
Container-title:International Journal of Mass Spectrometry
language:en
Short-container-title:International Journal of Mass Spectrometry

Author:

Nikcevic Irena,Wyrzykiewicz Tadeusz K.,Limbach Patrick A.

Funder

The National Institutes of Health

Publisher

Elsevier BV

Subject

Physical and Theoretical Chemistry,Spectroscopy,Condensed Matter Physics,Instrumentation

Reference31 articles.

1. Building oligonucleotide therapeutics using non-natural chemistries;Wilson;Curr. Opin. Chem. Biol.,2006

2. DNA-based therapeutics and DNA delivery systems: a comprehensive review;Patil;AAPS J.,2005

3. Recent advances in the stereocontrolled synthesis of antisense phosphorothioates;Lu;Mini Rev Med. Chem.,2006

4. Polymer solutions as a pseudostationary phase for capillary electrochromatographic separation of DNA diastereomers;Gilar;Electrophoresis,2000

5. Analytical study of phosphorothioate analogues of oligodeoxynucleotides using high-performance liquid chromatography;Agrawal;J. Chromatogr.,1990

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