Effect of the progestogens, gestodene, 3-keto desogestrel, levonorgestrel, norethisterone and norgestimate on the oxidation of ethinyloestradiol and other substrates by human liver microsomes

Author:

Back D.J.,Houlgrave R.,Tjia J.F.,Ward S.,L'e. Orme M.

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Endocrinology,Molecular Biology,Molecular Medicine,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference20 articles.

1. Metabolism of 17α-ethinylestradiol by human liver microsomes in vitro: aromatic hydroxylation and irreversible binding of metabolites;Bolt;J. Endocr. Metab.,1977

2. Catecholoestrogens (2- and 4-hydroxyestrogens)—chemistry, biogenesis, occurence and physiologic significance;Ball;Acta Endocr. Copenh.,1980

3. The biliary and urinary metabolites of [3H]17α-ethynylestradiol in women;Maggs;Xenobiotica,1983

4. The metabolism of 17αethinyloestradiol by human liver microsomes: formation of catechol and chemically reactive metabolites;Purba;Br. J. Clin. Pharmac.,1987

5. Oxidation of 17α-ethynylestradiol by human liver cytochrome P-450;Guengerich;Mol. Pharmac.,1988

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