The metabolism of 17 alpha-ethinyloestradiol by human liver microsomes: formation of catechol and chemically reactive metabolites.
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.1987.tb03074.x/fullpdf
Reference35 articles.
1. Estrogen 1,2-epoxides or estrogen quinones/semiquinones;Abdul-Hajj;Biochem. Biophys. Res. Comm.,1985
2. 2-Hydroxylation of ethinyloestradiol in relation to the oxidation of sparteine and antipyrine;Back;Br. J. clin. Pharmac.,1984
3. Catecholoestrogens (2- and 4-hydroxyoestrogens)-chemistry, biogenesis, occurrence and physiological significance;Ball;Acta. endocr. Copenh.,1980
4. Irreversible binding of ethinyloestradiol metabolites to protein and nucleic acids as catalysed by rat liver microsomes and mushroom tyrosinase;Bolt;J. steroid Biochem.,1974
5. Metabolism of 17α-ethinylestradiol by human liver microsomes in vitro: Aromatic hydroxylation and irreversible binding of metabolites;Bolt;J. endo-crinol. Metab.,1974
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